On the web server machine check to see if you have Administrators.txt file located in the following directory
If you see the file Administrators.txt remove the file from the App_Data folder and restart IIS or Default application pool.
Test again to see if Administrator can login and view settings page.
If that does not work create a file named Administrators.txt
in the file add entry with the users domain\name
Save File and place into C:\inetpub\wwwroot\panopticonex\App_Data
restart IIS or Default application pool.
Now log in using the user id you added to the Administrators.txt file.
They should now be able to view System Settings tab.